Igikoresho cya ogisijeni ni imashini itanga ogisijeni. Ihame ryayo rishingiye ku ikoranabuhanga ryo gutandukanya ikirere. Ubwa mbere, umwuka uhagarikwa kubwinshi. Noneho, ukoresheje uburyo butandukanye bwibice bigize ikirere, gaze - gutandukanya amazi bibaho mubushyuhe bwihariye. Hanyuma, distillation itandukanya umwuka muri ogisijeni na azote. Kubera ko ikoreshwa cyane cyane mu gukora ogisijeni, ikunze kwitwa ogisijeni. Bitewe n’imikoreshereze myinshi ya ogisijeni na azote, intumbero ya ogisijeni ikoreshwa cyane mu bukungu bw’igihugu, cyane cyane mu nganda nka metallurgie, inganda z’imiti, peteroli, ndetse n’ingabo.
Ubundi bwoko bwa ogisijeni ikoresha ibikoresho bya adsorption ya molekile ya sikeli. Binyuze mu mahame yumubiri kandi akoreshwa namavuta yo hejuru - amavuta yo kwimura - compressor yubusa, azote na ogisijeni mu kirere baratandukanijwe kugirango babone umwuka wa ogisijeni mwinshi. Ubu bwoko bwa ogisijeni butanga ogisijeni byihuse kandi murwego rwo hejuru, bigatuma bukenerwa no kuvura ogisijeni no kubungabunga ubuzima bwamatsinda atandukanye. Ifite ingufu nke, igura amafaranga 18 gusa kumasaha, kuyikoresha bihendutse.